Senior Director, Portfolio Strategy and Governance - Hematology

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
General Description:

The Senior Director, Portfolio Strategy and Governance - Hematology serves as a strategic leader and governance partner for the Hematology therapeutic area, working across R&D, Commercial, Finance, Program Management, and executive leadership to enable high-quality portfolio strategy and decision-making. This role translates disease-area strategy, development plans, competitive context, investment considerations, and operational dependencies into clear governance discussions and decision-ready recommendations.

The incumbent manages the Hematology Development Review Committee (Heme DRC) process as a core R&D governance forum, ensuring that topics are appropriately shaped, materials are robust, decisions are clearly documented, and follow-up actions are tracked through completion. The Senior Director also leads hematology input into annual portfolio strategy review and prioritization processes, helping senior leaders evaluate strategic choices, trade-offs, risks, value drivers, and resource implications.
Essential Functions of the Job:
Hematology Portfolio Governance

- Lead hematology portfolio governance for the Heme DRC and related senior forums by shaping agendas, working with Franchises, GPTs and DCTs in clarifying decision objectives, developing executive-ready materials, and ensuring discussions are decision-oriented and grounded in current scientific, clinical, competitive, operational, and financial context.

- Manage and continuously improve the Heme DRC operating model, including topic intake, agenda management, pre-read quality control, meeting facilitation, decision documentation, offline endorsements, minutes, action-item tracking, and progress reporting.

- Work with teams by providing clear processes in preparation for DRCs and executive governance forums, and for communication, escalation, and documentation to increase decision quality, transparency, and organizational follow-through.

Portfolio Strategy and Prioritization

- Partner with R&D and Commercial executive leaders to frame strategic hematology portfolio choices, including development-pathway options, processes for PTRS and TPP, investment sequencing, lifecycle opportunities, differentiation, resource implications, and prioritization trade-offs.

- Lead the hematology portion of the annual portfolio strategy review and portfolio prioritization process, ensuring discussions focus on strategic questions, disease-area priorities, cross-asset dependencies, value drivers, and investment or de-prioritization choices.

- Apply external benchmarks, competitor intelligence, and industry context to assess hematology portfolio differentiation, productivity, value, and investment priorities.

Executive Alignment and Communication

- Drive senior stakeholder alignment across Project Teams, Development and Franchise leadership, Commercial, Finance, Forecasting, Competitive Intelligence, Corporate Communications, Investor Relations, and Governance by identifying key decision points, risks, dependencies, and escalation needs.

- Support Board-level, executive, and external portfolio updates by synthesizing program progress, portfolio performance, emerging risks, strategic decision needs, and hematology portfolio narratives.

- Serve as a trusted strategic advisor to portfolio and governance leadership, bringing forward recommendations that improve decision quality and enable timely escalation of material issues.

Cross-Functional Partnership

- Work closely with program management teams supporting hematology oncology drug development and product lifecycle management to ensure governance decisions are informed by accurate and comprehensiv