Senior Director, Development AI Program Management

🏢 Ultragenyx · all Ultragenyx jobs
📍 United States
💰 USD 242,800 - 300,000 / annual
📅 Posted 2026-09-04 · via Himalayas
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Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx , we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx . We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team .

Position Summary:

ultra focused – Work together to fearlessly uncover new possibilities

The Senior Director, Development AI Program Management leads the delivery of Development’s highest-priority AI and operational transformation initiatives, turning enterprise AI capability into realized business value. Partnering closely with IT, the Development organization, and the AI Steering Committee, this leader prioritizes the portfolio, orchestrates cross-functional teams, and drives initiatives from concept through adoption on time, on scope, and to intended outcomes. They own end-to-end delivery accountability and provide ongoing quality, performance, and compliance oversight of deployed AI use cases across the Development lifecycle. This is a senior leadership role that builds the delivery engine and program discipline needed to scale responsible AI across Development
Work Model:

Remote: Officially documented as working full-time from home, with travel to Ultragenyx 's offices or other locations on occasion as needed.
Responsibilities:
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Portfolio prioritization. Partner with Development leaders and the AI Steering Committee to identify, evaluate, and prioritize AI and transformation initiatives against business value, feasibility, risk, and strategic fit, maintaining a clear, sequenced roadmap.

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Program & project leadership. Lead the end-to-end delivery of high-priority AI and operational transformation initiatives, coordinating across Development, IT, and other stakeholder from initiation through deployment and hand-off.

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Delivery accountability. Own scope, timeline, budget, resourcing, dependencies, and risk management; keep initiatives on track and resolve blockers to ensure predictable, on-time execution.

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Value realization. Define success metrics and business cases up front, then track, measure, and report realized value-efficiency, quality, and impact-against commitments after go-live.

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Business-to-technology partnership. Serve as the primary delivery interface to IT, translating business priorities into clear requirements and ensuring solutions are built on IT's platforms, standards, and scalable delivery model.

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Performance & compliance oversight. Provide ongoing quality oversight of deployed use-case performance; monitor outputs, drift, and adoption, and ensure solutions remain compliant with GxP, 21 CFR Part 11, and data governance requirements.

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Organizational change management. Lead adoption, training, and change management for delivered solutions so new AI-enabled workflows are embedded, sustained, and generating value across teams.

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Governance & reporting.

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