Principal AI Engineer

🏒 Velsera · all Velsera jobs (7)
πŸ“ United States
πŸ“… Posted 2026-09-10 Β· via Himalayas
🏷 Principal-AI-Engineer,AI-Platform-Engineering,Machine-Learning-Engineering,LLMOps-Engineering,AI-Infrastructure,AI-Principal-Engineer,Principal-AI-ML-Engineer,Principal-AI-Product-Engineer,Principal-ML-Engineer,Principal-AI-Systems-Engineer,Principal-Machine-Learning-Engineer,Principal-AI-Developer,Principal-AI-Architect,Lead-AI-Engineer
Apply on original site β†—

Principal AI Engineer β€” Velsera

AI Platform & Enablement Β· Reports to the CTO Β· Senior individual contributor
About the role

Velsera builds software and infrastructure for precision medicine β€” research platforms, clinical and diagnostic applications, and the systems that keep them running in regulated environments. We are adding AI capability across that portfolio and inside our own operations: governed model access, self-hosted and managed LLM serving, evaluation and audit, and integration into the products and business processes people already depend on.

This is a deliberately broad role. You will be deployed where the highest-value AI work is at the time β€” a customer-facing product capability in one quarter, an internal enterprise workflow in the next, a strategic account or funded program after that. The mandate stays the same wherever you land: design and ship production AI systems that hold up under real compliance requirements, work across AWS, Azure, and GCP, and leave behind reusable patterns rather than one-off builds.

You will set technical direction for what is expected to grow into an AI platform and enablement team.
What you'll work on
- Build a governed model access layer β€” self-hosted open-weight models, cloud-managed models (Bedrock, Vertex AI, Azure OpenAI), and customer- or partner-supplied models β€” designed to be consumed by more than one product or business function.

- Integrate AI capabilities into product experiences and enterprise workflows across batch, interactive, and agentic patterns.

- Establish the patterns everyone else reuses: evaluation, versioning, approvals, audit trails, cost control, guardrails, and safe rollout and rollback.

- Partner with product, engineering, security, QARA/compliance, IT, and scientific and commercial teams to introduce AI-native architectures that people can actually adopt.

- Move between assignments as business priorities shift, and make what you build in one part of the business usable in the next.

What you'll deliver (first 6–12 months)
- A production-ready, compliant AI/LLM serving and invocation layer that at least two products or business functions adopt β€” multi-tenant, auditable, and secure.

- A model governance workflow (intake, evaluation, approval, versioning, deprecation) that satisfies both regulated customers and our own quality system.

- Two or three AI capabilities shipped end to end in different parts of the business β€” for example a customer-facing product feature, an internal process automation, and assisted validation or compliance tooling.

- Integration patterns that preserve reproducibility, traceability, and standards alignment wherever the work lands.

- Operational readiness: monitoring, evaluation harnesses, incident playbooks, cost visibility, and measurable SLOs for key AI services.

- A defensible internal point of view on where we should build, buy, or not use AI at all β€” backed by what you shipped.

How we build (and what we'll expect you to optimize for)

You will make trade-offs in an environment that is multi-product, multi-cloud, standards-driven, and compliance-heavy. A few things matter a lot here:
- Reusability over one-offs. Design the second and third use case into the first one. A solution that only works for one product or one team is a partial solution.

- Standards and clean interfaces. Prefer open standards and well-defined boundaries over bespoke integrations.

- Multi-cloud, multi-deployment reality. AWS, Azure, and GCP are all in play, alongside customer-managed and self-hosted environments. Avoid hard dependencies on a single provider's AI stack.

- Security and auditability by default. Access control, logging, traceability, and data governance are part of the design, not add-ons.

- Reproducibility. AI features have to fit into workflows and processes that need to be repeatable and explainable, sometimes years later.

- Proportion. Ship the smallest thing that

← All remote jobs

Get remote jobs like this by email

One weekly digest. No spam, unsubscribe anytime.

Similar for you