Sr. Director of Sponsor Operations

CRIO is a leading provider of eSource solutions for clinical research. Our platform streamlines clinical data collection and management, ensuring protocol compliance and reducing errors. By eliminating paper binders and automating workflows, we help clinical trial sites and sponsors save time and money, improve data quality, and enhance patient safety. Our digital-first, site-centric approach supports virtual, hybrid, and traditional study structures, making clinical trials more efficient and effective.

Founded in 2015 by a clinical trial site owner seeking to improve his own business, today CRIO is the industry leader in site eSource with a fast-growing presence serving sponsors and CROs. CRIO is in use on 6000+ protocols at more than 2500 sites in 30 countries. In fact, the strength of our site community drives our growth which is why we place so much value on hands-on clinical research experience.
Position Summary

The Senior Director of Sponsor Operations is responsible for building, scaling, and leading CRIO’s enterprise sponsor business, including Central eSource programs across global pharmaceutical and CRO organizations.

This role owns the end to end sponsor lifecycle from initial engagement through multi study execution and long term expansion. The Head of Sponsor Operations ensures consistent, high quality delivery across all enterprise sponsor programs while establishing scalable operational frameworks that enable CRIO to grow its sponsor footprint effectively.

A critical component of this role is ownership of clinical data strategy and execution across sponsor programs, including data standards, integration alignment, data quality, and regulatory compliance. This individual ensures that CRIO’s eSource data is structured, mapped, validated, and delivered in a way that meets sponsor expectations and industry requirements.

Operating at the intersection of sponsor strategy, clinical operations, and technical data delivery, this role partners closely with Product, Engineering, and Customer Experience to align enterprise sponsor needs with CRIO’s platform capabilities and long term roadmap.
Key Responsibilities
Enterprise Sponsor Strategy and Growth

- Own the operational strategy for all enterprise sponsor programs including Lilly, ICON, Moderna, and future enterprise accounts

- Partner with Sales and Executive Leadership to support enterprise deal strategy, solution design, and expansion planning

- Define scalable Central eSource operating models across sponsor organizations

- Identify opportunities to expand sponsor adoption across additional studies, geographies, and use cases

Sponsor Portfolio Ownership and Execution

- Own delivery across all active and planned studies within enterprise sponsor portfolios

- Ensure consistency in execution, timelines, and quality across all sponsor engagements

- Establish standardized workflows, templates, and delivery frameworks across sponsors

- Drive visibility through executive level reporting on portfolio health, risks, and performance

- Establish governance models for enterprise sponsor accounts including regular executive reviews and QBR structures

- Serve as senior leadership point of contact for sponsor organizations

- Lead high level sponsor discussions related to scope, timelines, data expectations, and escalations

Clinical Data Strategy and Oversight

- Own the clinical data framework for all sponsor programs, ensuring alignment with industry standards and sponsor expectations

- Oversee CDASH mapping, data structuring, and standardization across all studies

- Ensure consistency and quality of data capture, validation, and downstream usability

- Define and enforce data governance practices across sponsor portfolios

- Oversee the alignment of eSource data with EDC systems, ensuring accurate, complete, and compliant data transfer

- Ensure integration outputs meet sponsor requirements for data quality, structure, and format

- Establish processe